Mpb Blastx Windows 10 Superlite [Bonus Inside]
Store the databases on an external NTFS drive but mount it inside WSL using drvfs . Alternatively, format a second partition as ext4 for direct Linux IO (faster than NTFS).
| Metric | Standard Windows 10 Pro (22H2) | Windows 10 Superlite + MPB BLASTX (WSL2) | | :--- | :--- | :--- | | OS RAM usage (idle) | 2.9 GB | 620 MB | | MPB BLASTX runtime (4 MPI) | 1 hour 48 minutes | 52 minutes | | Peak memory usage | 7.4 GB (thrashing) | 5.1 GB (stable) | | Failed queries (timeout) | 1,203 | 47 | | CPU throttling due to heat | After 15 minutes | After 40 minutes | mpb blastx windows 10 superlite
Enter the niche but powerful trifecta: , Windows 10 Superlite , and the BLASTX algorithm. This combination transforms modest hardware into a sequence-aligning workhorse. Store the databases on an external NTFS drive
# Download a mini database for testing (e.g., mouse mitochondria) update_blastdb.pl --decompress swissprot # Convert to MPB segmented format mpiformatdb -i swissprot -o swissprot_mpi -t 4 The Magic Flags A naive BLASTX command: slow. An optimized MPB BLASTX command: fast. Windows 10 Superlite
